Vitaran I (2 x 1ml) represents a high-purity polynucleotide (PN) injectable designed to elevate regenerative aesthetic treatments through superior tissue repair, hydration, and biological activation. As a part of the Vitaran PN product line, this formulation is specifically engineered to restore skin vitality by targeting the underlying causes of ageing such as cellular degradation, reduced fibroblast activity, compromised microcirculation, and ECM (extracellular matrix) breakdown. Unlike hyaluronic acid-based skin boosters, Vitaran I does not rely on volumisation; instead, it works by stimulating intrinsic cellular repair mechanisms to improve tissue quality from within.

Built on PDRN/PN technology, Vitaran I utilises ultra-purified DNA fragments known for their regenerative properties. These bioactive molecules promote fibroblast proliferation, stimulate collagen and elastin synthesis, and enhance DNA repair processes within the skin. The result is progressive improvement in skin texture, elasticity, firmness, and hydration. Patients experience smoother, brighter, and healthier-looking skin with a natural finish—without the risk of puffiness or the Tyndall effect.

Vitaran I is designed to treat wider facial and periocular areas, making it an excellent choice for patients concerned with early to moderate ageing signs. The formulation is especially effective for addressing dullness, crepey skin, fine lines, dehydration, pigment irregularities, and mild skin laxity. Through its regenerative action, Vitaran I improves microvascular circulation, reducing grey or tired appearance in the face and providing an overall revitalised complexion.

Its two 1ml sterile syringes offer enhanced flexibility for clinicians, enabling targeted placement across multiple anatomical areas in a single session. The product’s smooth consistency and favourable rheology allow practitioners to use various injection techniques—including microdroplet, mesotherapy, cannula placement, and linear threading—depending on the treatment and patient indication.

Another major advantage of Vitaran I is its suitability for combination therapies. Because it works through biological stimulation rather than volume creation, it can be combined safely with hyaluronic acid fillers, HA skin boosters, chemical peels, biorevitalisation systems, PRP, microneedling, or energy-based treatments. For clinics offering regenerative aesthetic protocols, Vitaran I integrates seamlessly into long-term anti-ageing treatment plans.

The results develop gradually as new collagen fibres form and dermal density increases. Patients typically observe improvements within 7–14 days post-treatment, with optimal results appearing after 2–3 sessions. Continued improvement may occur for up to 12 weeks due to ongoing tissue remodelling. Maintenance treatments every 6–9 months are recommended to sustain optimal outcomes.

Clinically, Vitaran I is known for its excellent safety profile. Because polynucleotides are highly biocompatible and derived from controlled DNA purification processes, the risk of adverse reactions is significantly lower compared to traditional injectables. The formulation’s ability to bind water molecules enhances long-term hydration while its anti-inflammatory properties help calm irritated or compromised skin. These characteristics make Vitaran I particularly suitable for sensitive or fragile skin types, including the thin and delicate areas around the eyes.

In summary, Vitaran I (2 x 1ml) is a sophisticated regenerative injectable crafted for multi-area facial rejuvenation. It embodies the principles of modern regenerative aesthetics—restoring skin health, rebuilding dermal tissue, and delivering natural, high-quality results. Its polynucleotide technology positions it as a premium product for clinics seeking to expand their offering of biologically active, non-surgical, long-lasting skin rejuvenation treatments.

Treatment Areas

• Full face

• Periocular region (non-volumising support)

• Tear trough texture improvement

• Fine lines and early wrinkles

• Neck and jawline

• Crepey or dehydrated skin

• Areas with reduced elasticity

Usage

• Inject via microdroplet, intradermal, mesotherapy, or cannula technique.

• Recommended protocol: 2–3 sessions, spaced 2–3 weeks apart.

• Maintenance every 6–9 months.

• Suitable as part of regenerative, combination, or biorevitalisation treatment plans.

Ingredient List

Polynucleotides (PN)

• 2 x 1ml high-purity polynucleotide syringes

• Promote cellular regeneration, fibroblast stimulation, collagen synthesis, hydration, and microcirculation repair.

Other components:

• Sterile isotonic solution optimised for biocompatibility.

Product Dimensions / Size

• 2 x 1ml sterile syringes

• Packaged for professional clinical use

Product Duration

• Effects last 6–9 months, depending on patient biology and treatment protocol.

Manufactured By

SKYBIO, South Korea

5 Popular Questions & Answers

1. What is Vitaran I used for?

Vitaran I is a polynucleotide-based injectable used for improving hydration, elasticity, texture, and overall skin regeneration. It targets early to moderate ageing signs and is suitable for face, neck, and periocular rejuvenation. It works by stimulating fibroblast activity and enhancing dermal repair.

2. How many treatments are required?

Most patients require 2–3 sessions spaced 2–3 weeks apart. Visible improvements start after the first session, but full regeneration occurs progressively as collagen and elastin production increase. Maintenance every 6–9 months ensures ongoing results.

3. Is Vitaran I suitable for sensitive skin?

Yes. Due to its high biocompatibility and anti-inflammatory properties, Vitaran I is safe for sensitive or fragile skin. Its gentle regenerative mechanism makes it well-suited for delicate areas like the eyes.

4. Can Vitaran I be combined with other treatments?

Absolutely. It works synergistically with HA fillers, microneedling, PRP, skin boosters, and energy-based treatments. Since it is non-volumising, it complements rather than competes with other modalities.

5. How does Vitaran I differ from HA-based boosters?

HA skin boosters hydrate and provide soft volume. Vitaran I focuses on biological rejuvenation—stimulating cellular repair, collagen production, and microcirculation improvement. It enhances tissue quality long-term rather than adding temporary plumpness.