Rejuran Polunucleotides 2x2ml

Rejuran Polynucleotides 2x2ml is a professional PN injectable skin booster from the Rejuran range, manufactured by PharmaResearch Co., Ltd. in South Korea. It is designed for use within professional aesthetic treatment protocols where the objective is to improve the appearance and quality of ageing or compromised skin.

Rejuran belongs to the rapidly expanding category of polynucleotide injectables, which have become increasingly popular within medical aesthetics as practitioners and patients seek treatment options focused on skin quality rather than traditional facial volumisation.

What is Rejuran?

Rejuran is based on polynucleotides (PN), purified DNA-derived molecules used within aesthetic medicine as a biostimulatory skin treatment. Rather than functioning primarily as a traditional dermal filler, Rejuran is designed around the concept of supporting the skin's natural regenerative environment.

This makes it particularly relevant for patients whose concerns include fine lines, reduced elasticity, uneven texture, dull-looking skin and visible signs of ageing, rather than patients who primarily require significant structural volume replacement.

The product is manufactured by PharmaResearch, a South Korean pharmaceutical and biotechnology company responsible for the Rejuran product family.

Polynucleotides and Skin Quality

Polynucleotides are long-chain DNA fragments that have been investigated for their biological and regenerative properties. Within aesthetic medicine, PN treatments are used with the aim of supporting skin regeneration, tissue quality and fibroblast activity.

The overall treatment concept is therefore different from that of conventional cross-linked HA fillers. A dermal filler is generally selected when a practitioner wants to restore volume, enhance projection or reshape a specific anatomical feature. A PN skin booster such as Rejuran is more focused on improving the quality and appearance of the skin itself.

For aesthetic practitioners, this distinction is important when selecting an appropriate treatment for an individual patient's concerns.

Rejuran as a Skin Booster

Rejuran can be incorporated into professional skin rejuvenation protocols for patients presenting with early to moderate visible signs of skin ageing.

Treatment objectives may include improvement in:

• Fine lines
• Skin texture
• Elasticity
• Hydration and overall skin appearance
• Dull or tired-looking skin
• Age-related skin-quality changes

The treatment is generally associated with a progressive approach to skin rejuvenation rather than a dramatic immediate change in facial shape.

This makes Rejuran particularly suitable for patients who prefer a natural-looking aesthetic outcome and want their skin to appear healthier and more refreshed without significant alteration of their facial contours.

Facial Rejuvenation

Rejuran can be considered as part of a comprehensive non-surgical facial rejuvenation programme. Depending on the patient's anatomy, skin condition and clinical objectives, practitioners may use PN treatment alongside other aesthetic procedures.

For example, a patient with significant volume depletion may require a conventional dermal filler to address structural loss, while a patient with adequate facial volume but poor skin quality may be better suited to a skin booster or biostimulatory treatment.

This allows practitioners to build personalised treatment plans rather than relying on one injectable product for every aspect of facial ageing.

Fine Lines and Skin Elasticity

Fine lines and reduced elasticity are common manifestations of chronological ageing and photoageing. As the skin's structural support changes, patients may notice increased fine lines, rougher texture and reduced firmness.

Rejuran's PN-based approach is intended to support the skin's biological environment and promote improvements in skin quality and elasticity over the course of treatment.

For clinics, this makes Rejuran particularly relevant for patients who are not necessarily looking for a volumising treatment but want to improve the overall appearance and condition of their skin.

Treatment Areas

The standard Rejuran formulation is associated with broader facial skin rejuvenation and can be considered for areas such as the cheeks, forehead, temples, perioral region and other areas of the face where skin-quality improvement is required.

The exact treatment area and injection technique should always be selected according to the manufacturer's current IFU and the practitioner's clinical assessment.

It is important to distinguish standard Rejuran from other products within the range. For example, Rejuran i is specifically designed for the delicate eye area, while other Rejuran formulations have different characteristics and intended applications.

Course-Based Treatment

PN skin boosters are commonly incorporated into course-based treatment programmes, rather than being considered a one-off permanent correction.

The number of treatments and intervals should be determined by the practitioner according to the patient's skin condition, treatment objectives and the current manufacturer's recommendations.

Individual results can vary considerably. Age, lifestyle, degree of photoageing, skin condition and biological response can all influence treatment outcomes.

Practitioners should therefore avoid guaranteeing a specific degree or duration of improvement.

Professional Patient Selection

Appropriate patient selection remains an essential part of any injectable aesthetic treatment.

Before administering Rejuran, practitioners should assess the patient's:

• Skin quality
• Degree of ageing
• Existing facial volume
• Previous injectable treatments
• Treatment expectations
• Relevant contraindications
• Condition of the proposed treatment area

Patients should receive appropriate consultation and informed consent before treatment.

Rejuran Compared with Dermal Fillers

One of the most important points when positioning Rejuran commercially is that it should not be presented as a conventional volumising dermal filler.

Cross-linked HA fillers are primarily used to restore or enhance volume, projection and contour. Rejuran is instead positioned within the polynucleotide skin booster category, where the primary objective is skin quality and rejuvenation.

This makes Rejuran complementary to, rather than necessarily interchangeable with, traditional dermal fillers.

Why Clinics Use Polynucleotide Treatments

The growing interest in polynucleotide skin boosters reflects increasing patient demand for subtle, progressive and natural-looking aesthetic treatments.

Patients are increasingly interested in improving the quality of their skin without significantly changing their facial proportions. A PN injectable can therefore form part of a broader treatment strategy focused on maintaining a healthy-looking and youthful appearance.

For aesthetic clinics, Rejuran provides an established product option within this expanding treatment category.

Professional Use

Rejuran should only be administered by appropriately qualified and trained healthcare professionals with suitable experience in injectable aesthetic medicine.

The practitioner should follow the current manufacturer's Instructions for Use (IFU) for preparation, administration, treatment areas, dosage, injection depth and treatment intervals.

As with all injectable procedures, appropriate aseptic technique and a detailed understanding of facial anatomy are essential.

Overall, Rejuran Polynucleotides 2x2ml provides aesthetic practitioners with a professional PN-based approach to skin rejuvenation. Its focus on skin quality, elasticity and fine-line improvement makes it a valuable option for clinics developing personalised non-surgical skin rejuvenation and injectable skin booster protocols.

Treatment Areas

Rejuran can be considered for professional treatment of facial areas including:

• Full face
• Forehead
• Cheeks
• Temples
• Perioral region
• Chin
• Lower face
• Areas affected by fine lines
• Areas showing reduced elasticity or compromised skin quality

For the delicate periocular region, practitioners should consider the formulation specifically indicated for that area, such as Rejuran i, and follow the applicable manufacturer documentation.

Usage

Rejuran Polynucleotides 2x2ml is supplied in pre-filled syringes for professional injectable use.

Treatment should only be performed by appropriately qualified practitioners experienced in aesthetic injectable procedures.

The appropriate injection technique, depth, dosage, treatment intervals and treatment protocol should be determined according to the current manufacturer's IFU and local regulatory requirements.

The treatment plan should be individualised according to the patient's skin condition, treatment goals and clinical assessment.

Ingredient ListPolynucleotides (PN)

The principal active component is purified polynucleotide (PN). Rejuran's PN technology is derived from highly purified DNA material and is used within aesthetic medicine as a biostimulatory skin treatment.

PN is intended to support the skin's regenerative environment and contribute to improvements in skin quality, elasticity and overall appearance.

Product Volume

2 × 2ml syringes

Total product volume: 4ml

The exact concentration and formulation should always be confirmed against the manufacturer's current packaging and IFU supplied with the product.

Product Dimensions / Size

2 × 2ml pre-filled syringes

• Product: Rejuran Polynucleotides
• Form: Injectable
• Quantity: 2 syringes
• Volume: 2ml per syringe
• Total volume: 4ml
• Category: Polynucleotide skin booster
• Manufacturer: PharmaResearch Co., Ltd.

Product Duration

The duration of results varies according to the patient's age, skin condition, lifestyle, degree of photoageing, treatment protocol and individual biological response.

Rejuran is generally incorporated into a course of treatments followed by maintenance according to clinical assessment. Practitioners should not promise a fixed duration of results, as individual treatment responses can differ.

Manufactured By

PharmaResearch Co., Ltd. — South Korea

PharmaResearch is the South Korean pharmaceutical and biotechnology company responsible for the Rejuran product range.
Frequently Asked Questions1. What is Rejuran Polynucleotides 2x2ml?

Rejuran Polynucleotides 2x2ml is a professional PN-based injectable skin booster manufactured by PharmaResearch in South Korea. It is designed for aesthetic skin rejuvenation and focuses on improving skin quality rather than providing the structural volume associated with traditional dermal fillers.

2. What is Rejuran used for?

Rejuran can be incorporated into professional facial rejuvenation protocols for patients concerned with fine lines, reduced elasticity, uneven texture and visible signs of skin ageing. Treatment should be individualised according to the patient's skin condition and the manufacturer's current product instructions.

3. Is Rejuran a dermal filler?

Rejuran is more appropriately classified as a polynucleotide skin booster / biostimulatory injectable rather than a conventional dermal filler. Its primary treatment objective is skin-quality improvement rather than significant facial volume enhancement.

4. How many Rejuran treatments are required?

Treatment requirements vary between patients. Rejuran is commonly incorporated into a course-based treatment programme, with treatment intervals and maintenance determined according to the patient's condition, clinical objectives and manufacturer's recommendations.

5. What is the difference between Rejuran and Rejuran i?

The main distinction is their intended treatment area. Rejuran is used for broader facial skin rejuvenation, while Rejuran i is specifically formulated for the delicate periocular/eye area. Practitioners should select the appropriate formulation according to the treatment area and current IFU.