PURI PDRN® – PDRN + Hyaluronic Acid Skin Booster | 5 × 2.5ml

PURI PDRN® – PDRN + Hyaluronic Acid Skin Booster | 5 × 2.5ml

Product Overview

PURI PDRN® is an advanced regenerative skin booster developed to support skin hydration, elasticity, firmness and overall skin quality through the combined benefits of Polydeoxyribonucleotide (PDRN) and cross-linked Hyaluronic Acid (HA).

Developed by Aeterderm in South Korea, PURI PDRN® combines 5mg/ml PDRN with 25mg/ml cross-linked Hyaluronic Acid in a professional formulation designed to provide intensive hydration while supporting the skin's natural regenerative processes.

Rather than functioning as a traditional dermal filler focused primarily on facial volume or structural augmentation, PURI PDRN® is designed to target skin quality from within.

The PDRN component is intended to support fibroblast activity, tissue regeneration and collagen synthesis, while Hyaluronic Acid provides intensive hydration and supports moisture retention within the treated tissue.

This combined approach makes PURI PDRN® particularly suited to professional skin-rejuvenation protocols where treatment objectives include improvements in:

• Skin hydration

• Elasticity

• Firmness

• Skin texture

• Skin smoothness

• Fine lines

• Dermal quality

• Skin radiance

• Overall skin revitalisation

PURI PDRN® may be incorporated into professional mesotherapy and regenerative aesthetic protocols following appropriate patient assessment and in accordance with the manufacturer's current Instructions for Use.

Pack Contents

Each pack contains:

• 5 × 2.5ml sterile ampoules of PURI PDRN®

• PDRN: 5mg/ml

• Cross-Linked Hyaluronic Acid: 25mg/ml

• Sterile, sealed professional-use packaging

Volume per Ampoule: 2.5ml

Total Pack Volume: 12.5ml

Always check the individual product packaging, manufacturer labelling and current Instructions for Use before administration.

Product Composition

PURI PDRN® combines PDRN and Hyaluronic Acid within a professional regenerative skin formulation.

Polydeoxyribonucleotide (PDRN) – 5mg/ml

PURI PDRN® contains 5mg/ml Polydeoxyribonucleotide (PDRN).

The supplied product information describes the PDRN as pharmaceutical-grade with a reported purity of 99.8%.

PDRN consists of bioactive DNA fragments and is incorporated into the formulation to support regenerative processes within the skin.

Its proposed role includes support for:

• Fibroblast activity

• Tissue regeneration

• Collagen synthesis

• Dermal repair

• Skin renewal

• Overall skin quality

Rather than providing physical volume, the PDRN component is intended to support biological processes associated with healthier and more resilient-looking skin.

Cross-Linked Hyaluronic Acid – 25mg/ml

PURI PDRN® also contains 25mg/ml cross-linked Hyaluronic Acid.

Hyaluronic Acid has a strong affinity for water and is incorporated to support intensive hydration and moisture retention within the skin.

The HA component is intended to support:

• Dermal hydration

• Moisture retention

• Skin elasticity

• Skin smoothness

• Improved texture

• Overall skin quality

Within PURI PDRN®, Hyaluronic Acid complements the regenerative properties of PDRN to provide a combined hydration and skin-rejuvenation approach.

Dual-Action PDRN + HA Rejuvenation

One of the defining characteristics of PURI PDRN® is the combination of regenerative PDRN with hydrating Hyaluronic Acid.

PDRN Regenerative Support

The PDRN component is designed to support:

• Fibroblast activity

• Tissue repair

• Skin regeneration

• Collagen synthesis

• Dermal renewal

Hyaluronic Acid Hydration

The HA component is designed to support:

• Intensive hydration

• Moisture retention

• Improved elasticity

• Skin softness

• Smoother-looking texture

Together, these components provide a dual-action approach focused on hydration + regenerative skin support.

This differentiates PURI PDRN® from conventional HA-only skin boosters and from structural dermal fillers.

PDRN & Skin Regeneration

Polydeoxyribonucleotide, commonly abbreviated to PDRN, is increasingly incorporated into professional regenerative aesthetic treatments where improvement in overall skin quality is the primary objective.

Within PURI PDRN®, PDRN is designed to support processes associated with tissue regeneration and dermal repair.

The supplied product information describes the PDRN component as supporting fibroblast stimulation and collagen synthesis.

Fibroblasts play an important role within the skin's extracellular matrix and are associated with the production and maintenance of structural components including collagen.

Supporting these regenerative processes may contribute to progressive improvements in:

• Skin firmness

• Elasticity

• Texture

• Dermal quality

• Fine lines

• Overall skin appearance

Unlike a conventional volumising filler, these changes are intended to develop progressively as part of the skin's regenerative response.

Intensive Hyaluronic Acid Hydration

Hydration plays an important role in maintaining healthy-looking skin, elasticity and smoothness.

PURI PDRN® contains 25mg/ml cross-linked Hyaluronic Acid, designed to support moisture retention within the treated tissue.

Improved hydration may contribute to:

• Softer-feeling skin

• Improved skin elasticity

• Smoother-looking texture

• Improved radiance

• Reduced appearance of dehydration-related fine lines

• Improved overall skin quality

The HA component therefore complements the regenerative action of PDRN by addressing hydration alongside skin renewal.

Key Benefits

• Advanced PDRN + HA regenerative skin booster

• 5 × 2.5ml professional pack

• 12.5ml total product volume

• Contains 5mg/ml PDRN

• Contains 25mg/ml cross-linked Hyaluronic Acid

• PDRN described as pharmaceutical-grade

• Reported 99.8% PDRN purity

• Combines regenerative support with intensive hydration

• Supports fibroblast activity

• Supports collagen production

• Supports tissue regeneration

• Supports dermal repair

• Provides intensive skin hydration

• Supports moisture retention

• Helps improve skin elasticity

• Helps improve skin firmness

• Supports smoother-looking skin

• Helps improve skin texture

• May reduce the appearance of fine lines and wrinkles

• May improve the appearance of enlarged pores

• Supports skin radiance and luminosity

• Supports overall skin renewal

• Suitable for preventative and corrective skin-rejuvenation programmes

• Designed for professional mesotherapy and regenerative aesthetic protocols

• Does not primarily function as a structural dermal filler

• Intended for appropriately qualified professional use

Common Treatment Areas

PURI PDRN® may be incorporated into professional skin-rejuvenation protocols targeting areas demonstrating dehydration, reduced elasticity or deterioration in overall skin quality.

Potential treatment areas described in the supplied product information include:

• Full face

• Neck

• Décolletage

• Hands

• Periorbital region

• Areas demonstrating skin laxity

• Areas requiring general skin rejuvenation

Treatment area suitability should always be determined following assessment of the patient's anatomy, skin quality, medical history and individual treatment objectives.

Particular care and appropriate professional competence are required when treating delicate anatomical areas such as the periorbital region.

Always follow the manufacturer's current Instructions for Use regarding approved indications, treatment areas, administration technique, treatment depth, product volume and placement.

PURI PDRN® vs Traditional HA Skin Boosters

Traditional Hyaluronic Acid skin boosters primarily focus on improving hydration and moisture retention.

PURI PDRN® combines Hyaluronic Acid with a PDRN component intended to provide additional regenerative support.

Traditional HA Skin Booster

Treatment objectives commonly include:

• Hydration

• Moisture retention

• Improved skin smoothness

• Improved elasticity

• General skin-quality enhancement

PURI PDRN®

The combined formulation is designed to support:

• Intensive hydration

• Moisture retention

• Fibroblast activity

• Collagen production

• Tissue regeneration

• Dermal repair

• Improved elasticity

• Improved firmness

• Improved texture

• Overall skin revitalisation

PURI PDRN® therefore provides a combined hydrating + regenerative approach to professional skin rejuvenation.

PURI PDRN® vs Structural Dermal Fillers

PURI PDRN® should not be considered equivalent to a conventional structural Hyaluronic Acid dermal filler.

Structural Dermal Fillers

Cross-linked HA fillers designed for structural augmentation primarily provide:

• Immediate physical volume

• Projection

• Structural support

• Facial contouring

• Correction of selected wrinkles and folds

PURI PDRN®

PURI PDRN® is designed primarily to support:

• Skin hydration

• Dermal regeneration

• Skin elasticity

• Skin firmness

• Skin texture

• Fine-line improvement

• Skin radiance

• Overall skin quality

The primary objective is therefore skin-quality improvement and regenerative support rather than facial volumisation or structural augmentation.

Recommended Treatment Course

The supplied product information describes a course of four treatment sessions as a commonly recommended approach.

A referenced treatment programme is:

• Initial Course: 4 treatments

• Treatment Interval: Approximately every 2–3 weeks

• Maintenance: Approximately every 3–4 months, or as clinically indicated

These intervals should not be interpreted as a universal treatment protocol.

Treatment planning should be individually determined according to:

• Patient age

• Baseline skin quality

• Degree of dehydration

• Skin elasticity

• Tissue condition

• Treatment area

• Medical history

• Previous aesthetic treatments

• Response to treatment

• Individual treatment objectives

The manufacturer's current Instructions for Use should always take precedence over general or commonly referenced treatment protocols.

Professional Treatment Considerations

PURI PDRN® is intended for administration by appropriately qualified and trained medical or aesthetic professionals with suitable knowledge of injectable skin-rejuvenation procedures.

Treatment planning should include:

• Comprehensive patient consultation

• Review of medical history

• Assessment of skin quality

• Assessment of tissue condition

• Evaluation of the proposed treatment area

• Review of previous aesthetic treatments

• Assessment of contraindications

• Discussion of realistic treatment expectations

• Explanation of potential adverse effects

• Appropriate documented informed consent

The appropriate treatment technique, depth, product volume and distribution should be determined according to individual anatomy, skin condition, practitioner assessment and the manufacturer's current Instructions for Use.

PURI PDRN® should not be administered using a generic treatment protocol without appropriate consideration of patient-specific factors.

Results & Treatment Outcomes

PURI PDRN® is designed to provide progressive skin-quality improvement through the combined effects of hydration and regenerative support.

The Hyaluronic Acid component supports hydration and moisture retention, while the PDRN component is intended to support the skin's regenerative processes.

Potential improvements may include:

• Increased skin hydration

• Improved skin radiance

• Smoother-looking skin

• Improved skin texture

• Improved elasticity

• Improved firmness

• Reduction in the appearance of fine lines

• Improvement in the appearance of enlarged pores

• Improved dermal quality

• Overall skin revitalisation

According to the supplied product information, improvements in hydration, radiance, smoothness and texture may become noticeable within the first few weeks following treatment.

Regenerative changes and collagen remodelling may continue progressively throughout an appropriate treatment course.

A complete professionally planned treatment course may therefore be recommended to maximise the intended skin-quality benefits.

Individual results vary according to:

• Patient age

• Baseline skin condition

• Treatment area

• Number of sessions

• Treatment interval

• Practitioner technique

• Lifestyle factors

• Individual biological response

Maintenance treatment may subsequently be considered following professional reassessment.

Storage & Handling

PURI PDRN® should be stored between:

2°C and 25°C

Protect the product from direct light and store according to the manufacturer's recommendations.

The supplied product information states a 24-month shelf life when stored appropriately.

To maintain product integrity:

• Keep the product within its original packaging until required.

• Store between 2°C and 25°C.

• Protect from direct light.

• Inspect each ampoule and the outer packaging before use.

• Check the batch number and expiry date.

• Verify product authenticity and traceability.

• Maintain appropriate aseptic handling procedures.

• Do not use if the sterile packaging has been compromised.

• Do not use if an ampoule appears damaged.

• Do not use after the stated expiry date.

Each ampoule should be used in accordance with the manufacturer's current Instructions for Use.

Important Information

PURI PDRN® is intended strictly for use by appropriately qualified and trained medical or aesthetic professionals.

Professional knowledge of the following is essential:

• Relevant anatomy

• Mesotherapy and injectable skin-rejuvenation techniques

• Appropriate treatment planes

• Patient selection

• Aseptic technique

• Complication prevention

• Adverse-event recognition

• Appropriate complication management

Patient Assessment

Treatment should only proceed following a full patient consultation, medical assessment and appropriate informed consent.

Patient assessment should consider:

• Medical history

• Previous aesthetic treatments

• Skin condition

• Treatment-area anatomy

• Allergies and hypersensitivities

• Active infection or inflammation

• Pregnancy or breastfeeding

• Relevant underlying medical conditions

• Individual treatment objectives

• Manufacturer-defined contraindications

Contraindications & Precautions

According to the supplied product information, treatment should not be performed in patients with:

• Active skin infection

• Known hypersensitivity to any product ingredient

• Pregnancy

• Breastfeeding

• Other contraindications identified following appropriate medical assessment

This list should not be considered exhaustive.

Always refer to the manufacturer's current Instructions for Use for the complete contraindication, warning and precaution profile.

Potential Treatment Reactions

As with injectable skin-rejuvenation procedures, temporary local treatment reactions may occur.

The exact adverse-event profile has not been provided in the supplied product information and should therefore be confirmed from the manufacturer's current Instructions for Use rather than inferred from other PDRN or skin-booster products.

Practitioners should provide patients with appropriate aftercare information and clear guidance regarding symptoms requiring professional or urgent medical assessment.

Do not use the product where:

• Sterile packaging is compromised

• An ampoule is damaged

• The product has passed its expiry date

• Product integrity is in doubt

• Authenticity or traceability cannot be established

Always consult the manufacturer's current Instructions for Use for complete information regarding indications, contraindications, warnings, precautions, administration and potential adverse events.

For appropriately qualified professional use only.