NeoGenesis® PDO Mono M2950 (29G x 50mm)

NEOGENESIS® PDO Mono M2950 – 20 Threads

NEOGENESIS® PDO Mono M2950 is a premium medical-grade Polydioxanone (PDO) mono thread developed to support collagen stimulation, skin rejuvenation, tissue strengthening and progressive improvement in skin firmness and quality.

Manufactured by NeoGenesis Co., Ltd. in South Korea, the M2950 combines a 29G × 50mm guide needle with a 70mm smooth PDO filament in USP 6-0. Its longer thread configuration makes it particularly suitable for professional treatment protocols involving larger facial and body areas where broader collagen stimulation and tissue coverage are desired.

Unlike cog or screw threads, the M2950 is a smooth, non-barbed monofilament designed primarily to stimulate a regenerative tissue response rather than mechanically lift or reposition tissue.

Once appropriately implanted within the tissues, the PDO filament acts as a temporary scaffold and initiates a controlled healing response associated with fibroblast activity, collagen formation and progressive tissue remodelling.

As the Polydioxanone gradually undergoes hydrolysis and is naturally absorbed by the body, the surrounding collagen response may continue to support improvements in skin firmness, elasticity, texture and overall tissue quality.

The longer 70mm filament provides greater treatment versatility than shorter mono threads, allowing appropriately trained practitioners to create broader collagen-supporting patterns across larger treatment areas.

Pack Contents

Each pack contains:

• 20 × sterile NEOGENESIS® PDO Mono Threads
• Model: M2950
• Needle Gauge: 29G
• Needle Length: 50mm
• PDO Thread Length: 70mm
• Thread USP: 6-0
• Smooth, non-barbed monofilament PDO thread
• Individually sterile blister packed
• Single-use only
• Sterile professional-use packaging

Each thread should remain sealed until immediately before treatment and must be stored, handled and used according to the manufacturer's current Instructions for Use.

Product Composition

Medical-Grade Polydioxanone (PDO)

The M2950 contains a smooth filament manufactured from medical-grade Polydioxanone, a fully absorbable synthetic polymer with an established history of use within absorbable surgical sutures.

Following implantation, PDO gradually undergoes hydrolysis within the tissues before being naturally absorbed.

During this period, the presence of the thread creates a controlled local tissue response associated with fibroblast activity, collagen formation and progressive tissue remodelling.

Medical-Grade Stainless Steel Guide Needle

Each PDO filament is supplied with a precision-manufactured stainless steel guide needle designed to facilitate controlled insertion and accurate thread placement by an appropriately trained practitioner.

The M2950 configuration comprises:

• 29G needle
• 50mm needle length
• 70mm PDO filament
• USP 6-0 thread

The product is sterile, biodegradable, biocompatible, latex-free and intended for single use only.

Mono Thread Technology

NEOGENESIS® PDO Mono M2950 is a classic smooth monofilament PDO thread developed primarily for collagen induction and skin revitalisation.

Unlike lifting threads that use barbs or cogs to engage and mechanically reposition tissue, mono threads work by creating a controlled tissue response around the implanted filament.

Over time, this response is designed to support the formation and reorganisation of collagen within the surrounding tissues, contributing to progressive improvements in skin quality.

The longer 70mm filament allows appropriately trained practitioners to:

• Cover broader treatment areas
• Create larger collagen-supporting treatment patterns
• Improve dermal density
• Strengthen ageing or weakened skin
• Support progressive improvement in skin firmness
• Support comprehensive facial and body rejuvenation protocols
• Complement other appropriately selected professional aesthetic treatments

Because the M2950 does not incorporate barbs or cogs, its primary purpose is biological tissue stimulation and skin-quality improvement rather than significant mechanical lifting.

PDO Collagen Stimulation

Following implantation, the PDO filament initiates a controlled local healing response that can stimulate natural regenerative processes within the surrounding tissues.

This response is associated with:

• Fibroblast activity
• Collagen production
• Elastin-related tissue remodelling
• Formation and reorganisation of connective tissue
• Progressive dermal remodelling
• Improved tissue quality

Rather than producing an immediate lifting effect, improvements associated with mono PDO threads are generally progressive as the surrounding tissues respond.

As the PDO filament gradually absorbs, the collagen-rich tissue response generated around the treatment area may continue to support improvements in firmness, elasticity and overall skin quality.

Longer 70mm PDO Filament

A key feature of the M2950 is its 70mm smooth PDO filament.

Compared with shorter mono thread configurations, the increased thread length provides practitioners with greater coverage across suitable facial and body treatment areas.

This makes the M2950 particularly useful where broader treatment patterns are required to support collagen induction and tissue quality.

Potential advantages of the longer filament include:

• Greater coverage across larger treatment areas
• Broader collagen-supporting treatment patterns
• Increased versatility for facial and body protocols
• Suitable for areas requiring longer linear placement
• Ability to complement shorter mono thread configurations
• Greater flexibility when designing individualised treatment patterns

Thread selection should always be based upon individual anatomy, tissue thickness, treatment area, desired outcome and the manufacturer's current Instructions for Use.

Key Benefits

• Premium medical-grade PDO mono thread
• Smooth, non-barbed monofilament design
• 29G × 50mm guide needle
• Longer 70mm PDO filament
• USP 6-0 thread
• 20 sterile threads per pack
• Longer configuration suitable for broader treatment areas
• Supports natural collagen production
• Encourages fibroblast activity
• Helps improve skin firmness
• Supports improved skin elasticity
• Helps improve dermal density
• Supports progressive skin tightening
• Helps improve skin texture
• May soften the appearance of fine lines
• Supports tissue regeneration and remodelling
• Designed for collagen-induction protocols
• Biodegradable and fully absorbable PDO
• Suitable for professionally assessed facial and body treatment areas
• Can complement shorter mono threads and other professional rejuvenation protocols
• Designed for skin-quality improvement rather than significant mechanical lifting
• Individually sterile blister packed
• Intended strictly for appropriately qualified professional use

Common Treatment Areas

Following appropriate consultation, professional assessment and confirmation within the manufacturer's current Instructions for Use, NEOGENESIS® PDO Mono M2950 may be incorporated into professional treatment protocols involving areas such as:

• Cheeks
• Mid-face
• Lower face
• Jawline
• Neck
• Décolletage
• Upper arms
• Abdomen
• Inner thighs
• Knees
• Back of the hands
• Selected areas of textural irregularity
• Areas of mild skin laxity
• Other authorised facial or body areas requiring collagen stimulation

The longer 70mm filament is particularly suitable where greater treatment coverage is beneficial.

Treatment suitability should always be determined according to the patient's anatomy, skin quality, tissue thickness, degree of laxity, medical history and individual treatment objectives.

Mono PDO threads are primarily intended to support collagen stimulation and skin-quality improvement rather than produce significant mechanical lifting.

Professional Treatment Considerations

The number of NEOGENESIS® PDO Mono M2950 threads required will vary according to:

• Treatment area
• Size of the treatment area
• Degree of skin laxity
• Desired level of collagen stimulation
• Skin and tissue thickness
• Individual anatomy
• Existing skin quality
• Previous aesthetic treatments
• Practitioner assessment

Treatment planning should include:

• Comprehensive medical consultation
• Assessment of facial or body anatomy
• Review of previous aesthetic procedures
• Evaluation of skin and tissue quality
• Assessment of contraindications
• Discussion of realistic treatment expectations
• Explanation of potential side effects and complications
• Appropriate documented informed consent

Thread placement, insertion depth, treatment pattern and total number of threads should always follow the manufacturer's current Instructions for Use together with appropriate product-specific training and professional clinical judgement.

Where clinically appropriate, the M2950 may form part of a broader professional rejuvenation programme alongside shorter mono threads, screw threads, cog threads, skin boosters, polynucleotides or collagen biostimulators.

The timing, sequencing and suitability of combination treatments should always be individually assessed.

Results & Longevity

Results from NEOGENESIS® PDO Mono M2950 treatment are generally progressive rather than based upon immediate mechanical lifting.

Patients may notice subtle changes in skin quality during the initial post-treatment period, with further improvements potentially developing as collagen-related tissue remodelling progresses.

Potential improvements may include:

• Improved skin firmness
• Enhanced elasticity
• Increased dermal density
• Improved skin texture
• Reduced appearance of fine lines
• Healthier-looking skin
• Improved overall skin quality
• Progressive improvement in areas of mild laxity
• Natural-looking rejuvenation

According to the supplied product information, PDO threads are gradually absorbed over approximately 6–8 months, while collagen remodelling may continue beyond the period of thread absorption.

Individual results and longevity will vary according to factors including:

• Patient age
• Baseline skin and tissue quality
• Treatment area
• Number and placement of threads
• Metabolism
• Lifestyle
• Practitioner technique
• Individual biological response

Maintenance or additional treatment may be considered following appropriate professional reassessment.

Important Information

NEOGENESIS® PDO Mono M2950 is intended strictly for use by qualified and appropriately trained medical or aesthetic professionals experienced in PDO thread procedures.

Professional knowledge of facial and body anatomy, tissue planes, vascular anatomy, aseptic technique, thread implantation procedures and complication prevention, recognition and management is essential.

Treatment should only proceed following:

• Full patient consultation
• Review of medical history
• Assessment of contraindications
• Examination of the proposed treatment area
• Assessment of skin and tissue quality
• Review of previous aesthetic procedures
• Discussion of expected outcomes and limitations
• Explanation of potential side effects and complications
• Appropriate documented informed consent

Treatment suitability must always be assessed according to the manufacturer's current Instructions for Use and individual patient circumstances.

Temporary treatment-related effects may include:

• Redness
• Swelling
• Bruising
• Tenderness
• Mild discomfort
• Localised tightness
• Minor temporary skin irregularity during healing
• Temporary asymmetry

More significant complications are possible with thread procedures, particularly where inappropriate placement or technique is used. These may include infection, thread migration, extrusion, prolonged discomfort, dimpling, nerve irritation, vascular injury or other adverse reactions requiring professional assessment and management.

Practitioners should possess appropriate training in PDO thread procedures and complication management and should provide patients with comprehensive written aftercare instructions.

Always consult the manufacturer's current Instructions for Use for complete indications, contraindications, precautions, warnings, permitted treatment areas and procedural guidance.

Store NEOGENESIS® PDO Mono M2950 according to the manufacturer's current recommendations.

Do not use if:

• The sterile blister packaging is damaged or compromised
• The product appears damaged
• The stated expiry date has passed
• Product integrity is in doubt
• Product authenticity cannot be verified

Each thread and guide needle is intended for single use only.

For professional use only.