Do I need a prescription to administer B12 injections in the UK?

Yes. Hydroxocobalamin and cyanocobalamin are prescription-only medicines (POMs) in the UK. You’ll need to work within a prescribing framework, either as an independent prescriber yourself or under a Patient Group Direction (PGD) or Patient Specific Direction (PSD) from a prescribing practitioner.

How often should clients have B12 injections?

This depends on the clinical picture. For clients with confirmed deficiency, the NHS loading dose protocol involves injections every other day for two weeks, followed by maintenance doses every three months. For wellness-focused clients without confirmed deficiency, many practitioners offer monthly injections, though this should be supported by appropriate assessment and documentation.

Can I administer B12 injections if I’m not a nurse or doctor?

Non-medically qualified practitioners can administer B12 injections, but only under a valid PGD or PSD signed off by an authorised prescriber. Always check your insurance covers this treatment and that you’re working within your scope of practice.

What’s the difference between hydroxocobalamin and methylcobalamin?

Hydroxocobalamin is the preferred form used in UK clinical practice. It’s the one recommended by NICE and the NHS. Methylcobalamin is popular in the wellness and functional medicine space but isn’t licensed in the UK in the same way. For clinical credibility and compliance, hydroxocobalamin is the safer choice for most practitioners.

How do I document B12 injections properly?

Thorough documentation should include a full medical history, any relevant blood test results (though not always mandatory), consent, the product used, batch number, site of injection, and any adverse reactions. Treat it the same way you’d document any injectable treatment, detailed, defensible, and stored securely.